Tris Buffer ��� Product identifier
Classification of the substance or mixture
The product is not classified, according to the Globally Harmonized System (GHS).
Label elements
GHS label elements Not Applicable
Hazard pictograms Not Applicable
Signal word Not Applicable
Hazard statements Not Applicable
Precautionary statements
Not a hazardous substance or mixture.
Classification system:
NFPA ratings (scale 0 ��� 4)
Health = 0
Fire = 0
Reactivity = 0
HMIS-ratings (scale 0 ��� 4)
Health = 0
Fire = 0
Reactivity = 0
Other hazards
Results of PBT and vPvB assessment
PBT: Not applicable.
vPvB: Not applicable.
1 Identification
2 Tris Buffer ��� Hazard(s) identification
REACTIVITY 0
FIRE 0
HEALTH 0
Chemical characterization: Mixtures
Description: Mixture of the substances listed below with nonhazardous additions.
Dangerous components: Not Applicable
Personal precautions, protective equipment and emergency procedures Not required.
Environmental precautions:
Do not allow to enter sewers.
Methods and material for containment and cleaning up:
Absorb with liquid-binding material (sand, diatomite, acid binders, universal binders, sawdust). Dispose contaminated material as waste according to section 13.
Reference to other sections
See Section 13 for disposal information.
Protective Action Criteria for Chemicals
Description of first aid measures
General information: No special measures required.
After inhalation: Supply fresh air.
After skin contact: Immediately take off contaminated clothing and rinse with water/shower.
After eye contact: Rinse eye for several minutes under running water. Then consult a doctor.
After swallowing: If symptoms persist consult doctor.
Information for doctor:
Most important symptoms and effects, both acute and delayed No further relevant information available.
Indication of any immediate medical attention and special treatment needed
No further relevant information available.
Extinguishing media
Suitable extinguishing agents: Water, Foam, Carbon Dioxide (CO2), Dry Powder.
Special hazards arising from the substance or mixture Carbon oxides, Nitrogen oxides, Hydrogen chloride gas.
Advice for firefighters
Protective equipment: In the event of fire, wear self-contained breathing apparatus.
3 Tris Buffer ��� Composition/information on ingredients
�� Table of Nonhazardous Ingredients
CAS: 77-86-1
Tris Hydroxymethyl Aminomethane (THAM)
100%
4 First-aid measures
5 Fire-fighting measures
6 Tris Buffer ��� Accidental release measures
�� PAC-1:
CAS: 77-86-1
Tris Hydroxymethyl Aminomethane (THAM)
18 mg/m��
Trade name: Tris Buffer
Handling:
Precautions for safe handling See section 2.2
Information about protection against explosions and fires: No special measures required.
Conditions for safe storage, including any incompatibilities
Storage: Tightly closed, Dry.
Requirements to be met by storerooms and receptacles: No special requirements.
Information about storage in one common storage facility: Not required.
Further information about storage conditions: None.
Specific end use(s) No further relevant information available.
�� PAC-2:
CAS: 77-86-1
Tris Hydroxymethyl Aminomethane (THAM)
190 mg/m��
�� PAC-3:
CAS: 77-86-1
Tris Hydroxymethyl Aminomethane (THAM)
1,200 mg/m��
7 Handling and storage
8 Tris Buffer ��� Exposure controls/personal protection
��
Additional information about design of technical systems: No further data; see section 7.
�� Control parameters
��
Components with limit values that require monitoring at the workplace:
The product does not contain any relevant quantities of materials with critical values that have to be monitored at the workplace.
��
Additional information: The lists that were valid during the creation were used as basis.
��
Exposure controls
��
Personal protective equipment:
��
General protective and hygienic measures:
The usual precautionary measures for handling chemicals should be followed.
��
Breathing equipment: Not required.
�� Protection of hands:
The glove material has to be impermeable and resistant to the product/ the substance/ the preparation.
Due to missing tests no recommendation to the glove material can be given for the product/ the preparation/ the chemical mixture.
Selection of the glove material on consideration of the penetration times, rates of diffusion and the degradation
�� Material of gloves
The selection of the suitable gloves does not only depend on the material, but also on further marks of quality and varies from manufacturer to manufacturer. As the product is a preparation of several substances, the resistance of the glove material can not be calculated in advance and has therefore to be checked prior to the application.
�� Penetration time of glove material
The exact break through time has to be found out by the manufacturer of the protective gloves and has to be observed.
��
Eye protection: Goggles recommended during refilling.
9 Physical and chemical properties
��
Information on basic physical and chemical properties
��
General Information
��
Appearance:
Form: Crystalline
Color: White
��
Odor: No data available
��
Odor threshold: Not determined.
�� pH-value: Not determined.
�� Change in condition
Melting point/Melting range: 165 ��� 170���
Boiling point/Boiling range: No data available
�� Flash point: Not applicable.
�� Flammability (solid, gaseous): Not applicable.
�� Decomposition temperature: Not determined.
�� Ignition temperature: No data available
�� Danger of explosion: No data available
�� Explosion limits:
Lower: Not determined.
Upper: Not determined.
�� Vapor pressure at 20 ��C (68 ��F): No data available)
�� Density at 20 ��C (68 ��F): 1.35 g/cm���
��
Relative density Not determined.
��
Vapor density Not determined.
��
Evaporation rate Not determined.
�� Solubility in / Miscibility with
Water: No data available
�� Partition coefficient (n-octanol/water): Not determined.
�� Viscosity:
Dynamic: Not determined.
Kinematic: Not determined.
�� Other information No further relevant information available.
�� Body protection: Protective work clothing
Reactivity No further relevant information available.
Chemical stability: The product is chemically stable under standard ambient conditions.
Thermal decomposition / conditions to be avoided: No decomposition if used according to specifications.
Possibility of hazardous reactions No dangerous reactions known.
Conditions to avoid No further relevant information available.
Incompatible materials: No further relevant information available.
Hazardous decomposition products: No dangerous decomposition products known.
Information on toxicological effects
Acute toxicity:
Primary irritant effect:
on the skin: No irritant effect.
on the eye: No irritating effect.
Sensitization: No sensitizing effects known.
Additional toxicological information:
The product is not subject to classification according to internally approved calculation methods for preparations:
When used and handled according to specifications, the product does not have any harmful effects according to our experience and the information provided to us.
Carcinogenic categories
Toxicity
Aquatic toxicity: No further relevant information available.
Persistence and degradability No further relevant information available.
Behavior in environmental systems:
Bioaccumulative potential No further relevant information available.
Mobility in soil No further relevant information available.
Additional ecological information:
General notes:
Water hazard class 1 (Self-assessment): slightly hazardous for water
Do not allow undiluted product or large quantities of it to reach ground water, water course or sewage system.
Results of PBT and vPvB assessment
PBT: Not applicable.
vPvB: Not applicable.
10 Stability and reactivity
11 Tris Buffer ��� Toxicological information
�� IARC (International Agency for Research on Cancer)
None of the ingredients is listed.
�� NTP (National Toxicology Program)
None of the ingredients is listed.
�� OSHA-Ca (Occupational Safety & Health Administration)
None of the ingredients is listed.
12 Ecological information
Waste treatment methods
Recommendation: Smaller quantities can be disposed of with household waste.
Uncleaned packagings:
Recommendation: Disposal must be made according to official regulations.
Recommended cleansing agent: Water, if necessary with cleansing agents.
Safety, health and environmental regulations/legislation specific for the substance or mixture
No further relevant information available.
Sara
13 Disposal considerations
14 Transport information
��
UN-Number
��
DOT, ADN, IMDG, IATA Not regulated
��
UN proper shipping name
��
DOT, ADN, IATA Not regulated
��
IMDG Not Regulated
Not regulated
��
Transport hazard class(es)
��
DOT, ADN, IMDG, IATA
��
Class Not regulated
��
Packing group
��
DOT, IMDG, IATA Not regulated
��
Environmental hazards:
��
Marine pollutant: No
�� Special precautions for user Not applicable.
�� Transport in bulk according to Annex II of MARPOL73/78 and the IBC Code Not applicable.
�� UN ���Model Regulation���: Not regulated
15 Tris Buffer ��� Regulatory information
�� Section 355 (extremely hazardous substances):
None of the ingredients is listed.
�� Section 313 (Specific toxic chemical listings):
None of the ingredients is listed.
�� TSCA (Toxic Substances Control Act):
Tris Hydroxymethyl Aminomethane (THAM)
ACTIVE
�� Other adverse effects No further relevant information available.
�� Proposition 65
�� Carcinogenic categories
GHS label elements Not Applicable
Hazard pictograms Not Applicable
Signal word Not Applicable
Hazard statements Not Applicable
Precautionary statements
If swallowed: Call a poison center/doctor if you feel unwell. If on skin: Wash with plenty of water.
If in eyes: Rinse cautiously with water for several minutes. Remove contact lenses, if present and easy to do. Continue rinsing.
Dispose of contents/container in accordance with local/regional/national/international regulations.
Chemical safety assessment: A Chemical Safety Assessment has not been carried out.
This information is based on our present knowledge. However, this shall not constitute a guarantee for any specific product features and shall not establish a legally valid contractual relationship.
Department issuing SDS: Environment protection department.
Date of preparation / last revision
Creation date for SDS. 29/05/2024.
Revision 1.0, 10/03/2025: Reviewed SDS for accuracy. MH/STN
�� Hazardous Air Pollutants
None of the ingredients is listed.
�� Chemicals known to cause cancer:
None of the ingredients is listed.
�� Chemicals known to cause reproductive toxicity for females:
None of the ingredients is listed.
�� Chemicals known to cause reproductive toxicity for males:
None of the ingredients is listed.
�� Chemicals known to cause developmental toxicity:
None of the ingredients is listed.
�� EPA (Environmental Protection Agency)
None of the ingredients is listed.
�� TLV (Threshold Limit Value)
None of the ingredients is listed.
�� NIOSH-Ca (National Institute for Occupational Safety and Health)
None of the ingredients is listed.
* 16 Other information
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